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Review Article

Journal of Digestive Cancer Research 2020; 8(2): 77-80

Published online December 31, 2020

© Korean Society of Gastrointestinal Cancer

아스피린 및 비스테로이드 소염제와 위암의 예방

Aspirin and Non-steroidal Anti-inflammatory Drugs in Prevention of Gastric Cancer

김연지, 정우철
Yeon-Ji Kim, Woo Chul Chung


가톨릭대학교 의과대학 내과학교실 성빈센트병원 소화기내과
Department of Internal Medicine, St. Vincent’s Hospital, The Catholic University of Korea College of Medicine, Suwon, Korea

Abstract

Gastric cancer is one of the leading causes of cancer-related deaths worldwide. The increased expression of cyclooxygenase (COX)-2 has been implicated in the development and progression of gastric cancers. A number of recent studies have been published evaluating the chemopreventive effect of aspirin and non steroidal anti inflammatory drungs (NSAIDs) against gastric cancer. Aspirin and NSAIDs use may reduce the risk of gastric cancer incidence and death, whereas other studies have reported contradictory results. Therefore, further study should be needed to clarify the role of aspirin and NSAIDs in the chemoprevention of gastric cancer.

KeywordsAnti-inflammatory agents Non-steroidal Aspirin Chemoprevention Low-dose Stomach neoplasia

Article

Review Article

Journal of Digestive Cancer Research 2020; 8(2): 77-80

Published online December 31, 2020

Copyright © Korean Society of Gastrointestinal Cancer Research.

아스피린 및 비스테로이드 소염제와 위암의 예방

김연지, 정우철

가톨릭대학교 의과대학 내과학교실 성빈센트병원 소화기내과

Aspirin and Non-steroidal Anti-inflammatory Drugs in Prevention of Gastric Cancer

Yeon-Ji Kim, Woo Chul Chung

Department of Internal Medicine, St. Vincent’s Hospital, The Catholic University of Korea College of Medicine, Suwon, Korea

Abstract

Gastric cancer is one of the leading causes of cancer-related deaths worldwide. The increased expression of cyclooxygenase (COX)-2 has been implicated in the development and progression of gastric cancers. A number of recent studies have been published evaluating the chemopreventive effect of aspirin and non steroidal anti inflammatory drungs (NSAIDs) against gastric cancer. Aspirin and NSAIDs use may reduce the risk of gastric cancer incidence and death, whereas other studies have reported contradictory results. Therefore, further study should be needed to clarify the role of aspirin and NSAIDs in the chemoprevention of gastric cancer.

Keywords: Anti-inflammatory agents, Non-steroidal, Aspirin, Chemoprevention, Low-dose, Stomach neoplasia

Journal Info

JDCR
Vol.12 No.1
April 20, 2024
eISSN : 2950-9505
pISSN : 2950-9394
Frequency: Triannual

open access

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Journal of Digestive Cancer Research

eISSN 2950-9505
pISSN 2950-9394

  • 2021
  • 2022
  • 2023
  • 2024