Journal of Digestive Cancer Research 2018; 6(2): 59-63
Published online December 31, 2018
© Korean Society of Gastrointestinal Cancer
Over the past decade, circulating tumor cell have received tremendous attention as new biomarkers and basic research subjects. In recent years, research on circulating tumor DNA, exosomes and microRNAs has also been actively conducted. These circulating tumor markers have the potential to become the basis of precision medicine, such as determining the genome / immune profile, monitoring response and tolerance, and selecting therapeutic agents beyond the early diagnosis and prognosis prediction. In this article, we introduce the diagnostic methods, efficacy, meaning, and applicability of various circulating tumor markers.
KeywordsCirculating tumor cell Precision medicine Liquid biopsy
Journal of Digestive Cancer Research 2018; 6(2): 59-63
Published online December 31, 2018
Copyright © Korean Society of Gastrointestinal Cancer Research.
한성용, 김동욱
부산대학교 의과대학 내과학교실, 부산대학병원 소화기내과
Sung Yong Han, Dong Uk Kim
Division of Gastroenterology and Hepatology, Department of Internal Medicine, and Biomedical Research Institute, Pusan National University Hospital, Pusan National University School of Medicine, Busan, Korea
Over the past decade, circulating tumor cell have received tremendous attention as new biomarkers and basic research subjects. In recent years, research on circulating tumor DNA, exosomes and microRNAs has also been actively conducted. These circulating tumor markers have the potential to become the basis of precision medicine, such as determining the genome / immune profile, monitoring response and tolerance, and selecting therapeutic agents beyond the early diagnosis and prognosis prediction. In this article, we introduce the diagnostic methods, efficacy, meaning, and applicability of various circulating tumor markers.
Keywords: Circulating tumor cell, Precision medicine, Liquid biopsy