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Review Article

Journal of Digestive Cancer Research 2016; 4(2): 83-87

Published online December 31, 2016

© Korean Society of Gastrointestinal Cancer

Optimal Indication of Prophylactic Cholecystectomy for Gallbladder Stones and Polyps in terms of Risk Factors of Gallbladder Cancer


Seung Eun Lee



Department of Surgery, Chung-Ang University College of Medicine, Seoul, Korea

Abstract

Till now, two distinct epithelial lesions, dysplasia and adenoma, are currently recognized as premalignant stages of gallbladder (GB) carcinogenesis. In these two carcinogenesis pathways, GB stones and polyps are regarded as one of the most important risk factors of GB carcinoma respectively. Although there still remain controversies for the indication of prophylactic cholecystectomy for GB stones and polyps due to lack of high-level evidence, the present review demonstrated that patients who have GB stones with more than 3 cm size, chronic typhoid carriers, porcelain GB, or anomalous pancreaticobiliary ductal union and patients with more than 1 cm sized GB polyp would be recommended prophylactic cholecystectomy.

KeywordsGallbladder Stone Polyp Carcinoma Cholecystectomy

Article

Review Article

Journal of Digestive Cancer Research 2016; 4(2): 83-87

Published online December 31, 2016

Copyright © Korean Society of Gastrointestinal Cancer Research.

Optimal Indication of Prophylactic Cholecystectomy for Gallbladder Stones and Polyps in terms of Risk Factors of Gallbladder Cancer

Seung Eun Lee

Department of Surgery, Chung-Ang University College of Medicine, Seoul, Korea

Abstract

Till now, two distinct epithelial lesions, dysplasia and adenoma, are currently recognized as premalignant stages of gallbladder (GB) carcinogenesis. In these two carcinogenesis pathways, GB stones and polyps are regarded as one of the most important risk factors of GB carcinoma respectively. Although there still remain controversies for the indication of prophylactic cholecystectomy for GB stones and polyps due to lack of high-level evidence, the present review demonstrated that patients who have GB stones with more than 3 cm size, chronic typhoid carriers, porcelain GB, or anomalous pancreaticobiliary ductal union and patients with more than 1 cm sized GB polyp would be recommended prophylactic cholecystectomy.

Keywords: Gallbladder, Stone, Polyp, Carcinoma, Cholecystectomy

Journal Info

JDCR
Vol.12 No.1
April 20, 2024
eISSN : 2950-9505
pISSN : 2950-9394
Frequency: Triannual

open access

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Journal of Digestive Cancer Research

eISSN 2950-9505
pISSN 2950-9394

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  • 2024