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Case Report

Journal of Digestive Cancer Research 2015; 3(1): 26-29

Published online June 30, 2015

© Korean Society of Gastrointestinal Cancer

A Case of Gastric Large Cell Neuroendocrine Carcinoma with Multiple Liver Metastasis Treated with Hepatic Artery Infusion Chemotherapy Followed by Surgery

김승범, 김국현, 김태년
Sung Bum Kim, Kook Hyun Kim, Tae Nyeun Kim



Department of Internal Medicine, Yeungnam University College of Medicine, Daegu, Korea

Abstract

A 73-year-old male visited our hospital with a complaint of general weakness. He underwent pyloric preserving pancreatoduodenectomy due to ampullary cancer three years ago. Abdominal computed tomography scan at initial visit revealed multiple hepatic masses. A PET-CT scan showed multiple FDG uptakes at whole liver. He underwent hepatic artery infusion chemotherapy (HAIC) for five cycles. During the first cycle of HAIC, he developed gastric ulcer bleeding and endoscopic hemostasis was done successfully. Esophagogastroduodenoscopy after the 5th cycle of HAIC revealed ulcer scar at gastric angle. PET-CT scan at 12 months showed no FDG uptake at liver, but a focal FDG uptakes at stomach and peri-gastric lymph nodes were newly developed. Esophagogastroduodenoscopy revealed about 3 cm sized mass at gastric angle. He underwent surgery and pathologic examination revealed large cell neuroendocrine carcinoma. We report a case of gastric large cell neuroendocrine carcinoma with liver metastasis treated with HAIC followed by surgery.

KeywordsNeuroendocrine carcinoma Liver metastasis Intra-arterial chemotherapy

Article

Case Report

Journal of Digestive Cancer Research 2015; 3(1): 26-29

Published online June 30, 2015

Copyright © Korean Society of Gastrointestinal Cancer Research.

A Case of Gastric Large Cell Neuroendocrine Carcinoma with Multiple Liver Metastasis Treated with Hepatic Artery Infusion Chemotherapy Followed by Surgery

Sung Bum Kim, Kook Hyun Kim, Tae Nyeun Kim

Department of Internal Medicine, Yeungnam University College of Medicine, Daegu, Korea

Abstract

A 73-year-old male visited our hospital with a complaint of general weakness. He underwent pyloric preserving pancreatoduodenectomy due to ampullary cancer three years ago. Abdominal computed tomography scan at initial visit revealed multiple hepatic masses. A PET-CT scan showed multiple FDG uptakes at whole liver. He underwent hepatic artery infusion chemotherapy (HAIC) for five cycles. During the first cycle of HAIC, he developed gastric ulcer bleeding and endoscopic hemostasis was done successfully. Esophagogastroduodenoscopy after the 5th cycle of HAIC revealed ulcer scar at gastric angle. PET-CT scan at 12 months showed no FDG uptake at liver, but a focal FDG uptakes at stomach and peri-gastric lymph nodes were newly developed. Esophagogastroduodenoscopy revealed about 3 cm sized mass at gastric angle. He underwent surgery and pathologic examination revealed large cell neuroendocrine carcinoma. We report a case of gastric large cell neuroendocrine carcinoma with liver metastasis treated with HAIC followed by surgery.

Keywords: Neuroendocrine carcinoma, Liver metastasis, Intra-arterial chemotherapy

Journal Info

JDCR
Vol.12 No.1
April 20, 2024
eISSN : 2950-9505
pISSN : 2950-9394
Frequency: Triannual

open access

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Journal of Digestive Cancer Research

eISSN 2950-9505
pISSN 2950-9394

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  • 2024