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Case Report

Journal of Digestive Cancer Research 2014; 2(2): 75-77

Published online December 31, 2014

© Korean Society of Gastrointestinal Cancer

항암화학요법과 수술을 통해 완전 관해를 획득한 진행성 십이지장 유두암 증례

A Case of Metastatic Ampulla of Vater Cancer Treated with Chemotherapy Followed by Pylorus Preserving Pancreaticoduodenectomy

윤해룡·정문재·방승민·박승우·송시영
Hae Ryong Yun, Moon Jae Chung, Seungmin Bang, Seung Woo Park, Si Young Song


연세대학교 의과대학 내과학교실
Division of Gastroenterology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea

Abstract

Ampulla of Vater (AOV) cancer is rare malignant tumor which arises within the vicinity of the AOV. Metastatic AOV adenocarcinoma has poor prognosis, with an overall survival rate at 2 years ranging from 5 to 10%. The Surveillance, Epidemiology and End Results Program of the National Cancer Institute indicated that lymph node metastasis was present in as many as half of patients which were associated with poor prognosis and liver was the second most common site of distant metastasis in AOV cancer. In this case report, we describe a case of complete resolution of AOV cancer, which was already spread to retroperitoneal lymph node and liver. The patient underwent gemcitabine plus cisplatin chemotherapy for palliative aim. After 12 month of chemotherapy, image study showed partial remission, so intraoperative radiofrequency ablation therapy and pylorus preserving pancreaticoduodenectomy was done. AOV cancer was completely resected and the patient was followed up without recurrence for 7 months.

KeywordsMetastatic ampulla of Vater cancer Chemotherapy Pylorus preserving pancreaticoduodenectomy Radiofrequency ablation therapy

Article

Case Report

Journal of Digestive Cancer Research 2014; 2(2): 75-77

Published online December 31, 2014

Copyright © Korean Society of Gastrointestinal Cancer Research.

항암화학요법과 수술을 통해 완전 관해를 획득한 진행성 십이지장 유두암 증례

윤해룡·정문재·방승민·박승우·송시영

연세대학교 의과대학 내과학교실

A Case of Metastatic Ampulla of Vater Cancer Treated with Chemotherapy Followed by Pylorus Preserving Pancreaticoduodenectomy

Hae Ryong Yun, Moon Jae Chung, Seungmin Bang, Seung Woo Park, Si Young Song

Division of Gastroenterology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea

Abstract

Ampulla of Vater (AOV) cancer is rare malignant tumor which arises within the vicinity of the AOV. Metastatic AOV adenocarcinoma has poor prognosis, with an overall survival rate at 2 years ranging from 5 to 10%. The Surveillance, Epidemiology and End Results Program of the National Cancer Institute indicated that lymph node metastasis was present in as many as half of patients which were associated with poor prognosis and liver was the second most common site of distant metastasis in AOV cancer. In this case report, we describe a case of complete resolution of AOV cancer, which was already spread to retroperitoneal lymph node and liver. The patient underwent gemcitabine plus cisplatin chemotherapy for palliative aim. After 12 month of chemotherapy, image study showed partial remission, so intraoperative radiofrequency ablation therapy and pylorus preserving pancreaticoduodenectomy was done. AOV cancer was completely resected and the patient was followed up without recurrence for 7 months.

Keywords: Metastatic ampulla of Vater cancer, Chemotherapy, Pylorus preserving pancreaticoduodenectomy, Radiofrequency ablation therapy

Journal Info

JDCR
Vol.12 No.1
April 20, 2024
eISSN : 2950-9505
pISSN : 2950-9394
Frequency: Triannual

open access

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Journal of Digestive Cancer Research

eISSN 2950-9505
pISSN 2950-9394

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