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Case Report

Journal of Digestive Cancer Research 2013; 1(2): 100-103

Published online November 1, 2013

© Korean Society of Gastrointestinal Cancer

위장관 간질종양의 수술 후 재발한 환자에서 발생한 Imatinib의
부작용과 효능 - 증례와 문헌고찰

Clinical Course and Side Effects of Imatinib in Recurrent Patient
after Surgical Resection of GIST - A Case and Literature Review

배정호·김광하·김동욱·이봉은·송근암
Jung Ho Bae, Gwang Ha Kim, Dong Uk Kim, Bong Eun Lee, Geun Am Song


부산대학교 의학전문대학원 내과학교실
Departments of Internal Medicine, Pusan National University School of Medicine, Busan, Korea

Abstract

A 79-year-old man was diagnosed with gastrointestinal stromal tumor (GIST) of the gastric cardia. We performed proximal
subtotal gastrectomy and started imatinib therapy as adjuvant treatment after surgery. Whole body skin rash
with urticaria was onset on 10 days after imatinib treatment, and the patient decided to stop imatinib because of
side effect. After 3 months, PET CT revealed GIST was recurred at spleen and abdominal lymph nodes, abdominal
wall. The patient was then restarted on imatinib therapy. On follow-up imaging studies, the tumor almost disappeared,
but both pleural effusion and pericardial effusion were found. In this paper, we describe a case of clinical course and
side effects in recurred GIST after adjuvant imatinib mesylate treatment.

KeywordsGIST Imatinib Side effect

Article

Case Report

Journal of Digestive Cancer Research 2013; 1(2): 100-103

Published online November 1, 2013

Copyright © Korean Society of Gastrointestinal Cancer Research.

위장관 간질종양의 수술 후 재발한 환자에서 발생한 Imatinib의
부작용과 효능 - 증례와 문헌고찰

배정호·김광하·김동욱·이봉은·송근암

부산대학교 의학전문대학원 내과학교실

Clinical Course and Side Effects of Imatinib in Recurrent Patient
after Surgical Resection of GIST - A Case and Literature Review

Jung Ho Bae, Gwang Ha Kim, Dong Uk Kim, Bong Eun Lee, Geun Am Song

Departments of Internal Medicine, Pusan National University School of Medicine, Busan, Korea

Abstract

A 79-year-old man was diagnosed with gastrointestinal stromal tumor (GIST) of the gastric cardia. We performed proximal
subtotal gastrectomy and started imatinib therapy as adjuvant treatment after surgery. Whole body skin rash
with urticaria was onset on 10 days after imatinib treatment, and the patient decided to stop imatinib because of
side effect. After 3 months, PET CT revealed GIST was recurred at spleen and abdominal lymph nodes, abdominal
wall. The patient was then restarted on imatinib therapy. On follow-up imaging studies, the tumor almost disappeared,
but both pleural effusion and pericardial effusion were found. In this paper, we describe a case of clinical course and
side effects in recurred GIST after adjuvant imatinib mesylate treatment.

Keywords: GIST, Imatinib, Side effect

Journal Info

JDCR
Vol.12 No.3
December 20, 2024
eISSN : 2950-9505
pISSN : 2950-9394
Frequency: Triannual

open access

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Journal of Digestive Cancer Research

eISSN 2950-9505
pISSN 2950-9394

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