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Case Report

Journal of Digestive Cancer Research 2013; 1(1): 53-57

Published online March 1, 2013

© Korean Society of Gastrointestinal Cancer

고립성 골 전이를 동반한 식도편평세포암에서 동시
항암화학방사선 요법 후 완전관해를 보인 1례

A Case of Complete Remission after Concurrent Chemoradiotherapy for
Esophageal Squamous cell Carcinoma with Solitary Bone Metastasis

이우진·전훈재·김예지·김선영·서민호·최혁순·김은선·금보라·진윤태·이홍식·엄순호·김창덕·류호상
Woo Jin Lee, Hoon Jai Chun, Ye Ji Kim, Sun Young Kim, Min Ho Seo,
Hyuk Soon Choi, Eun Sun Kim, Bora Keum, Yoon Tae Jeen, Hong Sik Lee,
Soon Ho Um, Chang Duck Kim, Ho Sang Ryu


고려대학교 의과대학 내과학교실
Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea

Abstract

There is no established treatment for esophageal carcinoma with metastasis. For the metastatic esophageal squamous
cell carcinoma, chemotherapy or best supportive care according to patient's performance status are accepted as an
available treatment. We report a case of complete remission after concurrent chemoradiotherapy for esophageal squamous
cell carcinoma with metastatic lesion in 5th thoracic vertebrae. A 57-year-old man with ongoing dysphagia and
weight loss was admitted to our hospital. On the endoscopic and radiologic imaging evaluation,the patient was diagnosed
as a squamous cell carcinoma of esophagus with solitary metastatic lesion in 5th thoracic vertebrae. The patient
was treated with combination chemotherapy (5-fluorouracil (5-FU) and cisplatin) and concurrent radiotherapy for two
months to relieve dysphagia. Because metastatic lesion in thoracic vertebrae was located near the primary esophageal
tumor, the metastatic lesion could be included within the radiation field. After concurrent chemoradiotherapy, consecutive
4 cycles of chemotherapy had been carried out. Primary esophageal tumor with metastatic lymph nodes and
metastatic lesion in 5th thoracic vertebrae disappeared on follow up computed tomography (CT) and positron emission
tomography-CT (PET-CT). Follow up endoscopic biopsy revealed no remnant malignant cells at previous primary cancer
lesion.

KeywordsEsophagus Carcinoma Metastatsis Concurrent Chemoradiotherapy

Article

Case Report

Journal of Digestive Cancer Research 2013; 1(1): 53-57

Published online March 1, 2013

Copyright © Korean Society of Gastrointestinal Cancer Research.

고립성 골 전이를 동반한 식도편평세포암에서 동시
항암화학방사선 요법 후 완전관해를 보인 1례

이우진·전훈재·김예지·김선영·서민호·최혁순·김은선·금보라·진윤태·이홍식·엄순호·김창덕·류호상

고려대학교 의과대학 내과학교실

A Case of Complete Remission after Concurrent Chemoradiotherapy for
Esophageal Squamous cell Carcinoma with Solitary Bone Metastasis

Woo Jin Lee, Hoon Jai Chun, Ye Ji Kim, Sun Young Kim, Min Ho Seo,
Hyuk Soon Choi, Eun Sun Kim, Bora Keum, Yoon Tae Jeen, Hong Sik Lee,
Soon Ho Um, Chang Duck Kim, Ho Sang Ryu

Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea

Abstract

There is no established treatment for esophageal carcinoma with metastasis. For the metastatic esophageal squamous
cell carcinoma, chemotherapy or best supportive care according to patient's performance status are accepted as an
available treatment. We report a case of complete remission after concurrent chemoradiotherapy for esophageal squamous
cell carcinoma with metastatic lesion in 5th thoracic vertebrae. A 57-year-old man with ongoing dysphagia and
weight loss was admitted to our hospital. On the endoscopic and radiologic imaging evaluation,the patient was diagnosed
as a squamous cell carcinoma of esophagus with solitary metastatic lesion in 5th thoracic vertebrae. The patient
was treated with combination chemotherapy (5-fluorouracil (5-FU) and cisplatin) and concurrent radiotherapy for two
months to relieve dysphagia. Because metastatic lesion in thoracic vertebrae was located near the primary esophageal
tumor, the metastatic lesion could be included within the radiation field. After concurrent chemoradiotherapy, consecutive
4 cycles of chemotherapy had been carried out. Primary esophageal tumor with metastatic lymph nodes and
metastatic lesion in 5th thoracic vertebrae disappeared on follow up computed tomography (CT) and positron emission
tomography-CT (PET-CT). Follow up endoscopic biopsy revealed no remnant malignant cells at previous primary cancer
lesion.

Keywords: Esophagus, Carcinoma, Metastatsis, Concurrent, Chemoradiotherapy

Journal Info

JDCR
Vol.12 No.1
April 20, 2024
eISSN : 2950-9505
pISSN : 2950-9394
Frequency: Triannual

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Journal of Digestive Cancer Research

eISSN 2950-9505
pISSN 2950-9394

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